"The ideal artificial lubricant should be preservative free; contain potassium, bicarbonate, and other electrolytes; and have a polymeric system to increase its retention time."*
Modern tear substitute preparations are entirely free of preservatives.
Phosphates in buffers can exert detrimental influence:
Eye drops that are used for treatment of dry eyes, particularly after ophthalmic surgery or injuries with epithelial damage, should not contain phosphate buffers.
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