The chronicles of the NEW HYLO DUAL INTENSE™ mini: against dry eye and inflammatory symptoms

As they say, ‘Time heals all wounds’. While this is often true, when it comes to dry eye, time can sometimes be a tricky partner. What starts as a mild discomfort or an irritating sensation may gradually become more pronounced, leading many to wonder, "How can these symptoms progress"?

At the heart of the dry eye disease lies a complex and potentially vicious cycle surrounding inflammation. Yet, understanding this cycle may be one of the essential steps towards managing and finding relief from chronic dry eye. While dry eye may turn out to be a persistent, chronic condition, it can be managed with adequate treatments from eye health professionals. 

Come along and delve with us to unveil the nature of dry eye disease and seek potential relief within reach. 

The Vicious Cycle of Dry Eye 

Dry eye arises from two primary reasons: insufficient tear production or rapid tear evaporation. [1] Such “eye drought” leads to hyperosmolarity – a high concentration of salt, proteins, and other molecules compared to the water (solvent). As a result, the cells on the surface of the eye begin to suffer and sustain damage. [2]

Increased friction between the eyelid and the dry eye surface, [3] coupled with mechanical irritation and cell damage, triggers a cascade of signals that initiate an inflammatory response. This inflammation further exacerbates the dryness and affects tear-producing glands, creating a vicious cycle of chronic dry eye and inflammation that can be challenging to break without proper treatment. [1,2]

A simple diagram showing the vicious cycle of dry eye disease. Modified from [2]

Escalating chronic dry eye and inflammatory symptoms such as itching and burning may leave you feeling uncomfortable: gritty sensations in the eyes throughout the day, potential vision problems, and impaired quality of life. You may find the experience overwhelming, even affecting your emotions! [1,3] While the complicated cycle of dry eye disease might be troublesome, you would be relieved to find that they may be a potential way to help address chronic dry eye symptoms.

Intensive relief for chronic dry eye and inflammatory symptoms

Among many, the use of lubricating eye drops/artificial tears may be a quick and efficient strategy for dry eye relief. Preservative-free and phosphate-free HYLO DUAL INTENSE™ mini and HYLO DUAL INTENSE™ are our most viscous lubricating eye drop for intensive relief of chronic dry eye and inflammatory symptoms. 

A high concentration of high molecular weight sodium hyaluronate provides long-lasting moisturization, [4] and the ectoine stabilizes the tear film against excessive tear evaporation and relieves inflammatory symptoms such as itching and burning. [5,6] This powerful combination of sodium hyaluronate and ectoine is the Gold Standard and a complete solution to chronic dry eye and inflammatory symptoms. 

Here is the really exciting news. Now, our NEW HYLO DUAL INTENSE™ mini makes it even easier to JUMP EARLY at chronic dry eye and inflammatory symptoms. An attractive mini price point with a starter pack size (150 drops, 5mL) is a great choice for patients who recently developed chronic dry eye or those who wish to experience HYLO DUAL INTENSE™! Finding relief with fewer daily applications has become much easier with HYLO DUAL INTENSE™ mini.  

You can find HYLO DUAL INTENSE™ mini and HYLO DUAL INTENSE™ Canada-wide at pharmacies and at optometry and ophthalmology clinics. 

Try HYLO DUAL INTENSE™ mini today and Feel the Difference! 

Should you have any concerns about your eye health, please consult with your eye health professional for medical assistance. 

CandorVision™ – Your eyes are everything! 

References: 

1. Craig JP, Nelson JD, Azar DT, Belmonte C, Bron AJ, Chauhan SK, de Paiva CS, Gomes JAP, Hammitt KM, Jones L, Nichols JJ, Nichols KK, Novack GD, Stapleton FJ, Willcox MDP, Wolffsohn JS, Sullivan DA. TFOS DEWS II Report Executive Summary. Ocul Surf. 2017 Oct;15(4):802-812. doi: 10.1016/j.jtos.2017.08.003. Epub 2017 Aug 8. PMID: 28797892. 

2. Baudouin C, Messmer EM, Aragona P, Geerling G, Akova YA, Benítez-del-Castillo J, Boboridis KG, Merayo-Lloves J, Rolando M, Labetoulle M. Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction. Br J Ophthalmol. 2016 Mar;100(3):300-6. doi: 10.1136/bjophthalmol-2015-307415. Epub 2016 Jan 18. PMID: 26781133; PMCID: PMC4789719. 

3. Golden MI, Meyer JJ, Zeppieri M, et al. Dry Eye Syndrome. [Updated 2024 Feb 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470411/ 

4. Müller-Lierheim WGK. Why Chain Length of Hyaluronan in Eye Drops Matters. Diagnostics (Basel). 2020 Jul 23;10(8):511. doi: 10.3390/diagnostics10080511. PMID: 32717869; PMCID: PMC7459843. 

5. Dwivedi M, Backers H, Harishchandra RK, Galla HJ. Biophysical investigations of the structure and function of the tear fluid lipid layer and the effect of ectoine. Part A: natural meibomian lipid films. Biochim Biophys Acta. 2014 Oct;1838(10):2708-15. doi: 10.1016/j.bbamem.2014.05.011. Epub 2014 May 17. PMID: 24841755.  

6. Dwivedi M, Brinkkötter M, Harishchandra RK, Galla HJ. Biophysical investigations of the structure and function of the tear fluid lipid layers and the effect of ectoine. Part B: artificial lipid films. Biochim Biophys Acta. 2014 Oct;1838(10):2716-27. doi: 10.1016/j.bbamem.2014.05.007. Epub 2014 May 20. PMID: 24853656.